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4. SUMMARY AND OUTLOOK
4.3 FUTURE PROSPECTS
In this work, C-PDMS was used as the thick electrode material. Although the thick electrodes
are easy to process, the conductivity is not as high as metals. With the continuous development
of MEMS technology, more materials and sophisticated processing methods can be used to make
thick electrodes, and the application of thick-electrode DEP in the eld of biological microuidics
can be further explored.
e multi-electrode structure of the thick-electrode DEP-single-cell 3D rotational chip also
has the problem that the chip is non-open structure, which makes trouble with single-cell recovery.
In addition, for 3D cell imaging, a more advanced algorithm can be developed to retrieve the in-
tracellular information (e.g. nuclear-to-cytoplasmic ratio and organelle structure) like what is done
for CT or MRI scanning, not limited to the morphology alone. At the same time, the cell activity
and functionality after the operation have not been studied in the current experiment.
e opto-electronic integration chip can be subsequently used for the separation of cell sam-
ples due to its multi-parameter measurement function. However, the optical ber core is small such
that the capture range is small. e problem greatly limits the eciency of capture and stretch. In
future work, it can be combined with other technical means to achieve the position control of the
cells in the microchannel, and improve the eciency of ber capture and stretch.
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