Python doesn't care if you use single quotes or double quotes to print a single statement. But, surely, both has some significance while printing complex statements, which we will see soon.

print "Hello World!" and print 'Hello World!' will give the same output Hello World! two times:

How will you print something like this:

print '''I am mad in love
                     do you think
                                 I am doing
                                           the right thing '''

Alternatively, you can also use double quotes three times to achieve the same thing:

print """I am mad in love
                     do you think
                                 I am doing
                                                                                                                             the right thing """

Let's try another example. What should be the outcome of the following statement?

print 'Hey there it's a cow'

The preceding piece of code gives the following results:

C:pydev>python hello.py
File "hello.py", line 1
print 'Hey there it's a cow'
^
SyntaxError: invalid syntax

Python simply interprets that the statement terminated with a single quote after it. The solution is to enclose the complete sentence within double quotes as shown:

print "Hey there it's a cow"

Adding double quotes (") gives an error-free output as shown:

C:pydev>python hello.py
Hey there it's a cow