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Book Description

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

Table of Contents

  1. Title Page
  2. Copyright Page
  3. Table of Contents
  4. About the Authors
  5. Preface
  6. Chapter 1. Introduction to the Resistance Problem
  7. Chapter 2. Working with Pathogens
  8. Chapter 3. A Survey of Antibiotics
  9. Chapter 4. Dosing to Cure
  10. Chapter 5. Emergence of Resistance
  11. Chapter 6. Movement of Resistance Genes Among Pathogens
  12. Chapter 7. Transmission of Resistant Disease
  13. Chapter 8. Surveillance
  14. Chapter 9. Making New Antibiotics
  15. Chapter 10. Restricting Antibiotic Use and Optimizing Dosing
  16. Chapter 11. Influenza and Antibiotic Resistance
  17. Chapter 12. Avoiding Resistant Pathogens
  18. Afterword: A Course of Action
  19. Appendix A. Molecules of Life
  20. Appendix B. Microbial Life Forms
  21. Glossary
  22. Literature Cited
  23. Index
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