This book is intended for people who are comfortable with at least the basics of TypeScript. If you know how to use the TypeScript Compiler, tsc, to build a config file and compile code, and the basics of things such as type safety, functions, and classes in TypeScript, then you should be able to get something out of this book.

If you have a more advanced understanding of TypeScript, then there should be plenty of material on technologies that you've not used before that will be of interest.