This chapter focuses on getting the best performance out of an OpenVPN setup. There are several parameters that can be tuned on both the server side and the client side for getting the highest throughput and the lowest latency. However, the optimal settings of these parameters largely depend on the network layout. The recipes in this chapter will therefore provide guidelines on how to tune these parameters and how to measure the increase or decrease in performance. These guidelines can then be applied to other network layouts to find the optimal performance.