- Cover image
- Title page
- Copyright
- Foreword
- List of Contributors
- Chapter 1. Cell Membrane Biology and Juxtacrine Signal Conversion
- 1.1 Introduction
- 1.2 Cell Membrane Biology—Early Milestones
- 1.3 Membrane Microdomains
- 1.4 Cell Membrane Emergence
- 1.5 Juxtacrine Signaling and Rewiring Cellular Networks
- 1.6 Protein Painting, Artificial Veto Cell Engineering
- 1.7 Trans Signal Conversion
- 1.8 Redirecting Juxtacrine Signals
- 1.9 Creating Auto-Signaling Loops
- 1.10 SCP Therapeutic Flexibility
- 1.11 The Cell Membrane Frontier
- References
- Chapter 2. Cell Surface Engineering by Chemical Reaction and Remodeling
- Chapter 3. Bioconjugation Reactions in Living Cells: Development, Advances, and Applications of Glycan-Specific Technologies
- Chapter 4. Pushing the Bacterial Envelope: Strategies for Re-Engineering Bacterial Surfaces with Heterologous Proteins and Sugars
- 4.1 Bacterial Surface Display
- 4.2 Strategies for Re-Engineering Bacterial Surfaces with Heterologous Proteins
- 4.3 Applications of Bacteria Expressing Heterologous Surface Proteins
- 4.4 Strategies for Re-Engineering Bacterial Surfaces with Heterologous Sugars
- 4.5 Applications of Bacteria Expressing Heterologous Surface Sugars
- 4.6 Conclusion
- Acknowledgment
- References
- Chapter 5. Noncovalent Functionalization of Cell Surface
- 5.1 Introduction
- 5.2 Methods of Cell Surface Engineering—Applications and Recent Developments
- 5.3 Electrostatic Interactions Mediated Cell Surface Modification
- 5.4 Advantages and Limitations of the Noncovalent Modification of the Cell Surface
- 5.5 Conclusions and Future Perspectives
- Acknowledgments
- References
- Chapter 6. Lipid-Mediated Cell Surface Engineering
- Chapter 7. Engineering the Surface of Cells Using Biotin–Avidin Chemistry
- Chapter 8. Construction and Computation with Nucleic Acids on the Cell Surface
- Chapter 9. Cell Surface Enzymatic Engineering-Based Approaches to Improve Cellular Therapies
- 9.1 Introduction
- 9.2 Use of Enzymes to Modify Cell Surface Carbohydrates on Proteins and Lipids to Enhance Migration to Tissues
- 9.3 Modification of Enzyme Activity Leads to Changes on Cell Surface Structures that Deter Migration and Metastasis
- 9.4 Use of Enzymes to Improve the Therapeutic Function of Cells Through Modification of the Cell Surface
- 9.5 Conclusion
- References
- Chapter 10. Cell Microencapsulation for Tissue Engineering and Regenerative Medicine
- Chapter 11. Cell Engineering with Nanoparticles for Cell Imaging
- Chapter 12. Micro/Nano-Engineering of Cells for Delivery of Therapeutics
- Chapter 13. Molecular Engineering of Cell and Tissue Surfaces with Polymer Thin Films
- Chapter 14. Biofunctionalization of Hydrogels for Engineering the Cellular Microenvironment
- Chapter 15. Probe and Control of Cell–Cell Interactions Using Bioengineered Tools
- Index
Micro- and Nanoengineering of the Cell Surface
Edited by
Jeffrey M. Karp
Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Weian Zhao
Sue and Bill Gross Stem Cell Research Center, Department of Pharmaceutical Sciences, University of California, Irvine, CA, USA
Micro & Nano Technologies Series
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