Table of Contents
Chapter 1. Cell Membrane Biology and Juxtacrine Signal Conversion
1.2 Cell Membrane Biology—Early Milestones
1.5 Juxtacrine Signaling and Rewiring Cellular Networks
1.6 Protein Painting, Artificial Veto Cell Engineering
1.8 Redirecting Juxtacrine Signals
1.9 Creating Auto-Signaling Loops
1.10 SCP Therapeutic Flexibility
1.11 The Cell Membrane Frontier
Chapter 2. Cell Surface Engineering by Chemical Reaction and Remodeling
2.2 Methods and Technology of Covalent Cell Surface Reaction
2.3 Relevance of Covalent Cell Surface Modification
3.2 Bioorthogonal Chemical Ligation Reactions for Glycan Labeling
3.3 Bioorthogonal Ligation Reactions: Exploitation in MOE-Based Applications
4.2 Strategies for Re-Engineering Bacterial Surfaces with Heterologous Proteins
4.3 Applications of Bacteria Expressing Heterologous Surface Proteins
4.4 Strategies for Re-Engineering Bacterial Surfaces with Heterologous Sugars
4.5 Applications of Bacteria Expressing Heterologous Surface Sugars
Chapter 5. Noncovalent Functionalization of Cell Surface
5.2 Methods of Cell Surface Engineering—Applications and Recent Developments
5.3 Electrostatic Interactions Mediated Cell Surface Modification
5.4 Advantages and Limitations of the Noncovalent Modification of the Cell Surface
5.5 Conclusions and Future Perspectives
Chapter 6. Lipid-Mediated Cell Surface Engineering
Chapter 7. Engineering the Surface of Cells Using Biotin–Avidin Chemistry
7.1 Introduction: Rationale for Engineering the Cell Surface
7.2 Biotin and Avidin: An Overview
7.3 Methods for Engineering Cell Surfaces with Avidin–Biotin Complexes
7.4 Applications of Cell Surface Engineering Using Avidin–Biotin Chemistry
Chapter 8. Construction and Computation with Nucleic Acids on the Cell Surface
8.1 Computation of Cell Identity
8.2 Targeted Transport of a Payload to a Cell Surface and Activation of Innate Cellular Response
8.3 DNA Channels and Pores Spanning Lipid Membrane
Chapter 9. Cell Surface Enzymatic Engineering-Based Approaches to Improve Cellular Therapies
Chapter 10. Cell Microencapsulation for Tissue Engineering and Regenerative Medicine
10.2 Encapsulation Requirements and Strategies
10.3 Materials Used for Cell Encapsulation
10.4 Therapeutic Applications of Encapsulated Cells
10.5 Challenges and Future Perspectives
Chapter 11. Cell Engineering with Nanoparticles for Cell Imaging
11.2 Imaging Modalities for NP Engineered Cells
11.3 Strategies for Cell Engineering with NPs
Chapter 12. Micro/Nano-Engineering of Cells for Delivery of Therapeutics
12.1 Cell Therapy—Success and Current Challenges
12.2 Cell Surface Engineering to Improve Cell Targeting
Chapter 13. Molecular Engineering of Cell and Tissue Surfaces with Polymer Thin Films
13.2 General Design Principles and Considerations
13.3 Cell Surface Engineering with Polymer Thin Films
Chapter 14. Biofunctionalization of Hydrogels for Engineering the Cellular Microenvironment
14.1 The 3D Extracellular Milieu
14.3 Engineering Degradability into Hydrogels
Chapter 15. Probe and Control of Cell–Cell Interactions Using Bioengineered Tools
15.2 In Vitro Study of Cell–Cell Interactions Using Engineered Microdevices
15.3 Probing and Manipulation of Cell–Cell Interactions Using Engineered Molecular Tools