Cover image for Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

Author Xueji Zhang , Haifeng Dong , Huang-Cheng Chang , Yuen Y. Hui
Release Date: 2019/01/01
ISBN: 9781119373452
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Book Description

A comprehensive reference on biochemistry, bioimaging, bioanalysis, and therapeutic applications of carbon nanomaterials

Carbon nanomaterials have been widely applied for biomedical applications in the past few decades, because of their unique physical properties, versatile functionalization chemistry, and biological compatibility. This book provides background knowledge at the entry level into the biomedical applications of carbon nanomaterials, focusing on three applications: bioimaging, bioanalysis, and therapy.

Carbon Nanomaterials for Bioimaging, Bioanalysis and Therapy begins with a general introduction to carbon nanomaterials for biomedical applications, including a discussion about the pros and cons of various carbon nanomaterials for the respective therapeutic applications. It then goes on to cover fluorescence imaging; deep tissue imaging; photoacoustic imaging; pre-clinical/clinical bioimaging applications; carbon nanomaterial sensors for cancer and disease diagnosis; targeted cancer therapy; and photothermal/photodynamic therapy. Each chapter briefly introduces the biomedical application and emphasizes the most appropriate carbon nanomaterial(s) for the application.

  • Provides an introduction to the biomedical applications of carbon nanomaterials for early-career scientists, as well as background and context for mid-career scientists and researchers
  • Contains four sections covering biochemistry, bioimaging, bioanalysis, and therapeutic applications of carbon nanomaterials
  • Presented by experts who have strong background in the field of nanotechnology for biomedical applications
  • Covers a hot area of research which has very unique physical properties, versatile functionalization chemistry, and biological compatibility

Carbon Nanomaterials for Bioimaging, Bioanalysis and Therapy is an excellent resource for academic researchers and industrial scientists working on preparation and bio-application of carbon nanomaterials, biomedical engineering, and nanotechnology.

Table of Contents

  1. Cover
  2. List of Contributors
  3. Series Preface
  4. Preface
    1. Structure of This Book
    2. Reference
  5. Part 1: Basics of Carbon Nanomaterials
    1. 1 Introduction to Carbon Structures
      1. 1.1 Carbon Age
      2. 1.2 Classification
      3. 1.3 Fullerene
      4. 1.4 Carbon Nanotubes
      5. 1.5 Graphene
      6. 1.6 Nanodiamonds and Carbon Dots
      7. Acknowledgment
      8. References
    2. 2 Using Polymers to Enhance the Carbon Nanomaterial Biointerface
      1. 2.1 Introduction
      2. 2.2 Colloidal Stability of CNMs
      3. 2.3 Functionalization of CNMs with Polymers
      4. 2.4 Influence of Polymers on the Spectral Properties of CNMs
      5. 2.5 Functionalizing CNMs with Antifouling Polymers for Bioapplications
      6. 2.6 Functionalization of CNMs with Stimuli‐Responsive Polymers
      7. 2.7 Functionalization of CNMs with Polymers for Delivery of Nucleic Acids
      8. 2.8 Outlook
      9. Acknowledgments
      10. References
    3. 3 Carbon Nanomaterials for Optical Bioimaging and Phototherapy
      1. 3.1 Introduction
      2. 3.2 Surface Functionalization of Carbon Nanomaterials
      3. 3.3 Carbon Nanomaterials for Optical Imaging
      4. 3.4 Carbon Nanomaterials for Phototherapies of Cancer
      5. 3.5 Conclusions and Outlook
      6. References
  6. Part II: Bioimaging and Bioanalysis
    1. 4 High‐Resolution and High‐Contrast Fluorescence Imaging with Carbon Nanomaterials for Preclinical and Clinical Applications
      1. 4.1 Introduction
      2. 4.2 Survey of Carbon Nanomaterials
      3. 4.3 Fluorescent Properties of FNDs and SWCNTs
      4. 4.4 Survey of High‐Resolution and High‐Contrast Imaging
      5. 4.5 Conclusions
      6. References
    2. 5 Carbon Nanomaterials for Deep‐Tissue Imaging in the NIR Spectral Window
      1. 5.1 Introduction
      2. 5.2 Carbon Nanomaterials for NIR Imaging
      3. 5.3 Conclusions and Outlook
      4. Acknowledgments
      5. References
    3. 6 Tracking Photoluminescent Carbon Nanomaterials in Biological Systems
      1. Chapter Summary
      2. 6.1 Introduction
      3. 6.2 Tracking Cells in Organisms with Fluorescent Nanodiamonds
      4. 6.3 Monitoring Inter and Intra Cellular Dynamics with Fluorescent Nanodiamonds
      5. 6.4 Single‐Walled Carbon Nanotubes: A Near‐Infrared Optical Probe of the Nanoscale Extracellular Space in Live Brain Tissue
      6. 6.5 Conclusion
      7. References
    4. 7 Photoacoustic Imaging with Carbon Nanomaterials
      1. Chapter Summary
      2. 7.1 Introduction
      3. 7.2 Photoacoustic Imaging Systems
      4. 7.3 Photoacoustic Application of Carbon Nanomaterials
      5. Acknowledgments
      6. References
    5. 8 Carbon Nanomaterial Sensors for Cancer and Disease Diagnosis
      1. 8.1 Introduction
      2. 8.2 Detection of VOC by Using Gas/Vapor Sensors for Cancer and Disease Diagnosis
      3. 8.3 Detection of Biomarkers Using Biosensors for Cancer and Disease Diagnosis
      4. 8.4 Conclusions and Perspectives
      5. Acknowledgments
      6. References
    6. 9 Recent Advances in Carbon Dots for Bioanalysis and the Future Perspectives
      1. 9.1 Introduction
      2. 9.2 Fundamentals of CDs
      3. 9.3 Bioengineering of CDs for Bioanalysis
      4. 9.4 Bioanalysis Applications of CDs
      5. 9.5 Future Perspectives
      6. 9.6 Conclusions
      7. References
  7. Part III: Therapy
    1. 10 Functionalized Carbon Nanomaterials for Drug Delivery
      1. 10.1 Introduction
      2. 10.2 Direct Fabrication of Graphene‐Based Composite with Photosensitizer for Cancer Phototherapy
      3. 10.3 Polyglycerol‐Functionalized Nanodiamond Conjugated with Platinum‐Based Drug for Cancer Chemotherapy
      4. 10.4 Polyglycerol‐Functionalized Nanodiamond Hybridized with DNA for Gene Therapy
      5. 10.5 Conclusions and Perspectives
      6. Acknowledgments
      7. References
    2. 11 Multifunctional Graphene‐Based Nanocomposites for Cancer Diagnosis and Therapy
      1. 11.1 Introduction
      2. 11.2 Multifunctional Graphene‐Based Composites for the Diagnosis/Therapy of Cancer
      3. 11.3 Multimodal Graphene‐Based Composites for the Radiotherapy of Cancer
      4. 11.4 Graphene‐Based Nanobiomaterials for Cancer Diagnosis
      5. 11.5 Conclusion
      6. Acknowledgment
      7. References
    3. 12 Carbon Nanomaterials for Photothermal Therapies
      1. 12.1 Introduction
      2. 12.2 GO for PTT
      3. 12.3 CNTs and CNHs for PTT
      4. 12.4 CDs and GDs for PTT
      5. 12.5 Fullerenes for PTT
      6. 12.6 Carbon Nanomaterial‐Based Nanocomposites for PTT
      7. 12.7 Carbon Nanomaterial‐Based Combined Therapy with PTT
      8. 12.8 Conclusions and Perspectives
      9. References
  8. Index
  9. End User License Agreement
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