To Utsav, our students and parents
—U. Maulik and
S. Bandyopadhyay
To my wife Lynn and
daughter Tiffany
—J. T. L. Wang
Dedication
by Jason T. Wang, Sanghamitra Bandyopadhyay, Ujjwal Maulik
Computational Intelligence and Pattern Analysis in Biological Informatics
- Cover
- Half Title page
- Title Page
- Copyright page
- Dedication
- Preface
- Contributors
- Part I: Introduction
- Part II: Sequence Analysis
- Part III: Structure Analysis
- Chapter 6: Structural Search in RNA Motif Databases
- Chapter 7: Kernels on Protein Structures
- Chapter 8: Characterization of Conformational Patterns in Active and Inactive Forms of Kinases Using Protein Blocks Approach
- 8.1 Introduction
- 8.2 Distinguishing conformational variations from rigid-body shifts in active and inactive forms of a kinase
- 8.3 Cross comparison of active and inactive forms of closely related kinases
- 8.4 Comparison of the active states of homologous kinases
- 8.5 Conclusions
- Acknowledgments
- References
- Chapter 9: Kernel Function Applications in Cheminformatics
- Chapter 10: In Silico Drug Design Using a Computational Intelligence Technique
- Part IV: Microarray Data Analysis
- Part V: Systems Biology
- Chapter 14: Techniques For Prioritization of Candidate Disease Genes
- 14.1 Introduction
- 14.2 Prioritization Based on Text-Mining with Reference to Phenotypes
- 14.3 Prioritization with no direct reference to phenotypes
- 14.4 Prioritization using interaction networks
- 14.5 Prioritization based on joint use of interaction network and literature-based similarity between phenotypes
- 14.6 Fusion of data from multiple sources
- 14.7 Conclusions and open problems
- 14.8 Acknowledgment
- References
- Chapter 15: Prediction of Protein–Protein Interactions
- Chapter 16: Analyzing Topological Properties of Protein–Protein Interaction Networks: A Perspective Toward Systems Biology
- Chapter 14: Techniques For Prioritization of Candidate Disease Genes
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