Start by compiling the shader pair into SPIR-V using the glslangValidator tool:

glslangValidator -G -o basic.vert.spv basic.vert.glsl
glslangValidator -G -o basic.frag.spv basic.frag.glsl

If successful, this produces the basic.vert.spv and basic.frag.spv SPIR-V output files.

To load your SPIR-V shaders into an OpenGL program, use glShaderBinary and glSpecializeShader. With glShaderBinary, use GL_SHADER_BINARY_FORMAT_SPIR_V as the binary format:

GLuint vertShader = glCreateShader(GL_VERTEX_SHADER);

// Load the shader into a std::vector
std::ifstream inStream("basic.vert.spv", std::ios::binary);
std::istreambuf_iterator<char> startIt(inStream), endIt;
std::vector<char> buffer(startIt, endIt);
inStream.close();

// Load using glShaderBinary
glShaderBinary(1, &vertShader, GL_SHADER_BINARY_FORMAT_SPIR_V, buffer.data(), buffer.size());

// Specialize the shader (specify the entry point)
glSpecializeShader( vertShader, "main", 0, 0, 0);

// Check for success/failure
GLint status;
glGetShaderiv(vertShader, GL_COMPILE_STATUS, &status);
if( GL_FALSE == status ) {
  // Loading failed...
}

The process is nearly exactly the same for the fragment shader; just use GL_FRAGMENT_SHADER instead of GL_VERTEX_SHADER on the first line.

Finally, we create the program object, attach the shaders, and link. This process is identical to that shown in the Linking a shader program recipe, so we won't reproduce it here.