Let's pretend that we need to disable that GPO link that was just established to the IT Department OU. We don't want to fully delete the link, because we plan to re-enable it again later, so we will simply issue a command to disable the link and make it inactive:
Set-GPLink "MyNewGPO" -target "ou=IT Department,dc=mydomain,dc=local" -LinkEnabled No
As you can guess, re-enabling this link is as simple as running the exact same command, but changing No to Yes at the end, as such:
Set-GPLink "MyNewGPO" -target "ou=IT Department,dc=mydomain,dc=local" -LinkEnabled Yes