Home Page Icon
Home Page
Table of Contents for
Measuring agreement
Close
Measuring agreement
by Haikady N. Nagaraja, Pankaj K. Choudhary
Measuring Agreement
PREFACE
CHAPTER 1 INTRODUCTION
1.1 PREVIEW
1.2 NOTATIONAL CONVENTIONS
1.3 BASIC CHARACTERISTICS OF A MEASUREMENT METHOD
1.4 METHOD COMPARISON STUDIES
1.5 MEANING OF AGREEMENT
1.6 A MEASUREMENT ERROR MODEL
1.7 SIMILARITY VERSUS AGREEMENT
1.8 A TOY EXAMPLE
1.9 CONTROVERSIES AND OUR VIEW
1.10 CONCEPTS RELATED TO AGREEMENT
1.11 ROLE OF CONFIDENCE INTERVALS AND HYPOTHESES TESTING
1.12 COMMON MODELS FOR PAIRED MEASUREMENTS DATA
1.13 THE BLAND-ALTMAN PLOT
1.14 COMMON REGRESSION APPROACHES
1.15 INAPPROPRIATE USE OF COMMON TESTS IN METHOD COMPARISON STUDIES
1.16 KEY STEPS IN THE ANALYSIS OF METHOD COMPARISON DATA
1.17 CHAPTER SUMMARY
1.18 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 2 COMMON APPROACHES FOR MEASURING AGREEMENT
2.1 PREVIEW
2.2 INTRODUCTION
2.3 MEAN SQUARED DEVIATION
2.4 CONCORDANCE CORRELATION COEFFICIENT
2.5 A DIGRESSION: TOLERANCE AND PREDICTION INTERVALS
2.6 LIN’S PROBABILITY CRITERION AND BLAND-ALTMAN CRITERION
2.7 LIMITS OF AGREEMENT
2.8 TOTAL DEVIATION INDEX AND COVERAGE PROBABILITY
2.9 INFERENCE ON AGREEMENT MEASURES
2.10 CHAPTER SUMMARY
2.11 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 3 A GENERAL APPROACH FOR MODELING AND INFERENCE
3.1 PREVIEW
3.2 MIXED-EFFECTS MODELS
3.3 A LARGE-SAMPLE APPROACH TO INFERENCE
3.4 MODELING AND ANALYSIS OF METHOD COMPARISON DATA
3.5 CHAPTER SUMMARY
3.6 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 4 PAIRED MEASUREMENTS DATA
4.1 PREVIEW
4.2 MODELING OF DATA
4.3 EVALUATION OF SIMILARITY AND AGREEMENT
4.4 CASE STUDIES
4.5 CHAPTER SUMMARY
4.6 TECHNICAL DETAILS
4.7 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 5 REPEATED MEASUREMENTS DATA
5.1 PREVIEW
5.2 INTRODUCTION
5.3 DISPLAYING DATA
5.4 MODELING OF DATA
5.6 EVALUATION OF REPEATABILITY
5.7 CASE STUDIES
5.8 CHAPTER SUMMARY
5.9 TECHNICAL DETAILS
5.10 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 6 HETEROSCEDASTIC DATA
6.1 PREVIEW
6.2 INTRODUCTION
6.3 VARIANCE FUNCTION MODELS
6.4 REPEATED MEASUREMENTS DATA
6.5 PAIRED MEASUREMENTS DATA
6.6 CHAPTER SUMMARY
6.7 TECHNICAL DETAILS
6.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 7 DATA FROM MULTIPLE METHODS
7.1 PREVIEW
7.2 INTRODUCTION
7.3 DISPLAYING DATA
7.4 EXAMPLE DATASETS
7.5 MODELING UNREPLICATED DATA
7.6 MODELING REPEATED MEASUREMENTS DATA
7.7 MODEL FITTING AND EVALUATION
7.8 EVALUATION OF SIMILARITY AND AGREEMENT
7.9 EVALUATION OF REPEATABILITY
7.10 CASE STUDIES
7.11 CHAPTER SUMMARY
7.12 TECHNICAL DETAILS
7.13 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 8 DATA WITH COVARIATES
8.1 PREVIEW
8.2 INTRODUCTION
8.3 MODELING OF DATA
8.4 EVALUATION OF SIMILARITY, AGREEMENT, AND REPEATABILITY
8.5 CASE STUDY
8.6 CHAPTER SUMMARY
8.7 TECHNICAL DETAILS
8.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 9 LONGITUDINAL DATA
9.1 PREVIEW
9.2 INTRODUCTION
9.3 MODELING OF DATA
9.4 EVALUATION OF SIMILARITY AND AGREEMENT
9.5 CASE STUDY
9.6 CHAPTER SUMMARY
9.7 TECHNICAL DETAILS
9.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 10 A NONPARAMETRIC APPROACH
10.1 PREVIEW
10.2 INTRODUCTION
10.3 THE STATISTICAL FUNCTIONAL APPROACH
10.4 EVALUATION OF SIMILARITY AND AGREEMENT
10.5 CASE STUDIES
10.6 CHAPTER SUMMARY
10.7 TECHNICAL DETAILS
10.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 11 SAMPLE SIZE DETERMINATION
11.1 PREVIEW
11.2 INTRODUCTION
11.3 THE SAMPLE SIZE METHODOLOGY
11.4 CASE STUDY
11.5 CHAPTER SUMMARY
11.6 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 12 CATEGORICAL DATA
12.1 PREVIEW
12.2 INTRODUCTION
12.3 EXPERIMENTAL SETUPS AND EXAMPLES
12.4 COHEN’S KAPPA COEFFICIENT FOR DICHOTOMOUS DATA
12.5 KAPPA TYPE MEASURES FOR MORE THAN TWO CATEGORIES
12.6 CASE STUDIES
12.7 MODELS FOR EXPLORING AGREEMENT
12.8 DISCUSSION
12.9 CHAPTER SUMMARY
12.10 BIBLIOGRAPHIC NOTE
EXERCISES
REFERENCES
DATASET LIST
INDEX
EULA
Search in book...
Toggle Font Controls
Playlists
Add To
Create new playlist
Name your new playlist
Playlist description (optional)
Cancel
Create playlist
Sign In
Email address
Password
Forgot Password?
Create account
Login
or
Continue with Facebook
Continue with Google
Sign Up
Full Name
Email address
Confirm Email Address
Password
Login
Create account
or
Continue with Facebook
Continue with Google
Prev
Previous Chapter
Introduction
Next
Next Chapter
PREFACE
Contents
PREFACE
CHAPTER 1 INTRODUCTION
1.1 PREVIEW
1.2 NOTATIONAL CONVENTIONS
1.3 BASIC CHARACTERISTICS OF A MEASUREMENT METHOD
1.4 METHOD COMPARISON STUDIES
1.5 MEANING OF AGREEMENT
1.6 A MEASUREMENT ERROR MODEL
1.7 SIMILARITY VERSUS AGREEMENT
1.8 A TOY EXAMPLE
1.9 CONTROVERSIES AND OUR VIEW
1.10 CONCEPTS RELATED TO AGREEMENT
1.11 ROLE OF CONFIDENCE INTERVALS AND HYPOTHESES TESTING
1.12 COMMON MODELS FOR PAIRED MEASUREMENTS DATA
1.13 THE BLAND-ALTMAN PLOT
1.14 COMMON REGRESSION APPROACHES
1.15 INAPPROPRIATE USE OF COMMON TESTS IN METHOD COMPARISON STUDIES
1.16 KEY STEPS IN THE ANALYSIS OF METHOD COMPARISON DATA
1.17 CHAPTER SUMMARY
1.18 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 2 COMMON APPROACHES FOR MEASURING AGREEMENT
2.1 PREVIEW
2.2 INTRODUCTION
2.3 MEAN SQUARED DEVIATION
2.4 CONCORDANCE CORRELATION COEFFICIENT
2.5 A DIGRESSION: TOLERANCE AND PREDICTION INTERVALS
2.6 LIN’S PROBABILITY CRITERION AND BLAND-ALTMAN CRITERION
2.7 LIMITS OF AGREEMENT
2.8 TOTAL DEVIATION INDEX AND COVERAGE PROBABILITY
2.9 INFERENCE ON AGREEMENT MEASURES
2.10 CHAPTER SUMMARY
2.11 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 3 A GENERAL APPROACH FOR MODELING AND INFERENCE
3.1 PREVIEW
3.2 MIXED-EFFECTS MODELS
3.3 A LARGE-SAMPLE APPROACH TO INFERENCE
3.4 MODELING AND ANALYSIS OF METHOD COMPARISON DATA
3.5 CHAPTER SUMMARY
3.6 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 4 PAIRED MEASUREMENTS DATA
4.1 PREVIEW
4.2 MODELING OF DATA
4.3 EVALUATION OF SIMILARITY AND AGREEMENT
4.4 CASE STUDIES
4.5 CHAPTER SUMMARY
4.6 TECHNICAL DETAILS
4.7 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 5 REPEATED MEASUREMENTS DATA
5.1 PREVIEW
5.2 INTRODUCTION
5.3 DISPLAYING DATA
5.4 MODELING OF DATA
5.6 EVALUATION OF REPEATABILITY
5.7 CASE STUDIES
5.8 CHAPTER SUMMARY
5.9 TECHNICAL DETAILS
5.10 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 6 HETEROSCEDASTIC DATA
6.1 PREVIEW
6.2 INTRODUCTION
6.3 VARIANCE FUNCTION MODELS
6.4 REPEATED MEASUREMENTS DATA
6.5 PAIRED MEASUREMENTS DATA
6.6 CHAPTER SUMMARY
6.7 TECHNICAL DETAILS
6.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 7 DATA FROM MULTIPLE METHODS
7.1 PREVIEW
7.2 INTRODUCTION
7.3 DISPLAYING DATA
7.4 EXAMPLE DATASETS
7.5 MODELING UNREPLICATED DATA
7.6 MODELING REPEATED MEASUREMENTS DATA
7.7 MODEL FITTING AND EVALUATION
7.8 EVALUATION OF SIMILARITY AND AGREEMENT
7.9 EVALUATION OF REPEATABILITY
7.10 CASE STUDIES
7.11 CHAPTER SUMMARY
7.12 TECHNICAL DETAILS
7.13 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 8 DATA WITH COVARIATES
8.1 PREVIEW
8.2 INTRODUCTION
8.3 MODELING OF DATA
8.4 EVALUATION OF SIMILARITY, AGREEMENT, AND REPEATABILITY
8.5 CASE STUDY
8.6 CHAPTER SUMMARY
8.7 TECHNICAL DETAILS
8.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 9 LONGITUDINAL DATA
9.1 PREVIEW
9.2 INTRODUCTION
9.3 MODELING OF DATA
9.4 EVALUATION OF SIMILARITY AND AGREEMENT
9.5 CASE STUDY
9.6 CHAPTER SUMMARY
9.7 TECHNICAL DETAILS
9.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 10 A NONPARAMETRIC APPROACH
10.1 PREVIEW
10.2 INTRODUCTION
10.3 THE STATISTICAL FUNCTIONAL APPROACH
10.4 EVALUATION OF SIMILARITY AND AGREEMENT
10.5 CASE STUDIES
10.6 CHAPTER SUMMARY
10.7 TECHNICAL DETAILS
10.8 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 11 SAMPLE SIZE DETERMINATION
11.1 PREVIEW
11.2 INTRODUCTION
11.3 THE SAMPLE SIZE METHODOLOGY
11.4 CASE STUDY
11.5 CHAPTER SUMMARY
11.6 BIBLIOGRAPHIC NOTE
EXERCISES
CHAPTER 12 CATEGORICAL DATA
12.1 PREVIEW
12.2 INTRODUCTION
12.3 EXPERIMENTAL SETUPS AND EXAMPLES
12.4 COHEN’S KAPPA COEFFICIENT FOR DICHOTOMOUS DATA
12.5 KAPPA TYPE MEASURES FOR MORE THAN TWO CATEGORIES
12.6 CASE STUDIES
12.7 MODELS FOR EXPLORING AGREEMENT
12.8 DISCUSSION
12.9 CHAPTER SUMMARY
12.10 BIBLIOGRAPHIC NOTE
EXERCISES
REFERENCES
DATASET LIST
INDEX
EULA
Guide
Cover
Title page
Copyright
List of Tables
Chapter 1
Table 1.1
Interpretation of test theory terms in the context of method comparison studies under the measurement error model (1.6).
Table 1.2
Plasma volume measurements expressed as a percentage of normal values due to Hurley and Nadler (data originally provided by C. Doré, see Cotes et al., 1986).
Table 1.3
Potato weights (grams) data for Exercise 1.6.
Table 1.4
IPI angle (
◦
) data for Exercise 1.8.
Table 1.5
Fat content (g/100ml) data for Exercise 1.9.
Chapter 2
Table 2.1
Oxygen consumption (ml/kg/min) data for Exercise 2.3.
Chapter 4
Table 4.1
Summary of estimates of bivariate normal model parameters and measures of similarity and agreement for oxygen saturation data. Lower bound for CCC and upper bound for TDI are presented. Methods 1 and 2 refer to OSM and pulse, respectively.
Table 4.2
Summary of estimates of model parameters and measures of similarity and agreement for log-scale plasma volume data. Lower bound for CCC and upper bound for TDI are presented. Methods 1 and 2 refer to Hurley and Nadler methods, respectively.
Table 4.3
Summary of estimates of bivariate normal model parameters and measures of similarity and agreement for vitamin D data. Lower bound for CCC and upper bound for TDI are presented.
Table 4.4
Cardiac output (l/min) data for Exercise 4.8.
Chapter 5
Table 5.1
Summary of estimates of model parameters and measures of similarity, repeatability, and agreement for kiwi data. Lower bounds for CCC and upper bounds for TDI are presented. Methods 1 and 2 refer to micrometer and microscope, respectively.
Table 5.2
Summary of estimates of model parameters and measures of similarity, repeatability, and agreement for the oximetry data. Lower bounds for CCC and upper bounds for TDI are presented. Methods 1 and 2 refer to pulse oximetry and CO-oximetry, respectively.
Table 5.3
Kiwi data consisting of eggshell thickness measurements (in
μ
m). They are provided by P. Cassey, see Igic et al. (2010).
Table 5.4
Knee joint angle (in degrees) data for Exercise 5.8.
Table 5.5
Cardiac ejection fraction (in %) data for Exercise 5.9 (data provided by L. S. Bowling, see Bowling et al., 1993).
Table 5.6
Peak expiratory flow rate (in l/min) data for Exercise 5.10.
Table 5.7
Coronary artery calcium score data for Exercise 5.11.
Chapter 6
Table 6.1
Summary of parameter estimates for cholesterol data. Methods 1 and 2 refer to Cobas Bio and Ektachem, respectively.
Table 6.2
Summary of parameter estimates for cyclosporin data. Methods 1 and 2 refer to HPLC and RIA, respectively.
Chapter 7
Table 7.1
Summary of parameter estimates for systolic blood pressure data. Methods 1, 2, 3, and 4 refer to the observers MS1, MS2, MS3, and DS, respectively.
Table 7.2
Estimates and 95% simultaneous confidence intervals for all-pairwise bias differences and precision ratios for systolic blood pressure data. Methods 1, 2, 3, and 4 refer to the observers MS1, MS2, MS3, and DS, respectively.
Table 7.3
Estimates and one-sided 95% simultaneous confidence bounds for all-pairwise CCCs and TDIs (with
p
= 0.90) for systolic blood pressure data. Methods 1, 2, 3, and 4 refer to the observers MS1, MS2, MS3, and DS, respectively.
Table 7.4
Summary of parameter estimates for tumor size data.
Table 7.5
Estimates and 95% simultaneous confidence intervals for all-pairwise bias differences and modified precision ratios for tumor size data.
Table 7.6
Estimates and one-sided 95% individual confidence bounds for repeatability versions of CCC and TDI (0.90) for tumor size data.
Table 7.7
Estimates and 95% one-sided simultaneous confidence bounds for all-pairwise values of CCC and TDI (0.90) for tumor size data.
Table 7.8
Fractional area change measurements (in %) for Exercise 7.9.
Chapter 8
Table 8.1
Summary of estimates of parameters of Models A (with variance covariate) and B (with mean and variance covariates) for blood pressure data. Methods 1 and 2 refer to mercury sphygmomanometer and automatic monitor, respectively.
Chapter 9
Table 9.1
Summary of estimates of model parameters for percentage body fat data. Methods 1 and 2 refer to caliper and DEXA, respectively.
Chapter 10
Table 10.1
Nonparametric and parametric estimates for measures of similarity and agreement for unreplicated blood pressure data. The parametric estimates are based on the bivariate normal model (4.6). Lower bounds for CCC and upper bounds for TDI are presented. Methods 1 and 2 refer to arm and finger methods, respectively.
Table 10.2
Estimates and two-sided 95% simultaneous confidence intervals for all-pairwise mean differences and variance ratios for replicated blood pressure data. Methods 1, 2, and 3 refer to observers J and R and the monitor, respectively.
Table 10.3
Estimates and one-sided 95% simultaneous confidence bounds for all-pairwise CCCs and TDIs (with
p
= 0.90) for replicated blood pressure data. Methods 1, 2, and 3 refer to observers J and R and the monitor, respectively.
Table 10.4
Crab claws data consisting of lengths of crab claws (in mm) for Exercise 10.16. They are provided by P. Cassey.
Chapter 11
Table 11.1
Expected standard errors for estimators of various measures.
Chapter 12
Table 12.1
Observed conclusions of randomized clinical trials and preceding meta analyses.
Table 12.2
Summary of observed responses of physicians and nurses on medical and surgical cases flagged by the CSP system.
Table 12.3
Diagnosis by two neurologists of patients on the likelihood of multiple sclerosis.
Table 12.4
Summary of observed responses of raters 1 and 2.
Table 12.5
Fitness-to-drive evaluation data for Exercise 12.13.
Table 12.6
Frequencies of observed classifications for disease classification data for Exercise 12.15.
Table 12.7
Frequencies of observed evaluations of six psychiatrists for 30 patients for Exercise 12.17.
List of Illustrations
Chapter 1
Figure 1.1
Scatterplots of simulated paired measurements data with high correlations superimposed with the line of equality. (a) The methods have perfect agreement. (b) The methods have unequal means but equal variances. (c) The methods have unequal variances but equal means. (d) The methods have unequal means and variances.
Figure 1.2
Scatterplots (panels (a) and (c)) and Bland-Altman plots (panels (b) and (d)) for two simulated datasets. The line of equality and the zero line are, respectively, superimposed on the two plots.
Figure 1.3
Plots for oxygen saturation data. Panel (a): Scatterplot with line of equality. Panel (b): Bland-Altman plot with zero line.
Figure 1.4
Scatterplots and Bland-Altman plots for plasma volume data. Panels (a) and (b) show measurements on original scale (%); panels (c) and (d) show log-scale measurements. The line of equality and the zero line are, respectively, superimposed on the two plots.
Figure 1.5
Scatterplots and Bland-Altman plots for vitamin D data. Panels (a) and (b) show measurements on original scale (ng/mL); panels (c) and (d) show log-scale measurements. The line of equality and the zero line are, respectively, superimposed on the two plots.
Figure 1.6
Variations of the usual Bland-Altman plot. Panel (a): Plot of ratio versus average for plasma volume data. Panel (b): Plot of relative difference versus average for vitamin D data. The horizontal lines in the plots, respectively, mark the points 1 and 0.
Figure 1.7
A scatterplot of simulated data superimposed with the line of equality, around which the data are truly scattered, and the true regression line of
Y
2
on
Y
1
.
Figure 1.8
Vertical and perpendicular distances of a data point from a line. The former is used in ordinary least squares whereas the latter is used in orthogonal least squares.
Figure 1.9
Deming regression line and the two ordinary least squares regression lines for the data displayed in Figure 1.7.
Figure 1.10
Trellis plot of log-scale plasma volume data. The subjects are sorted according to their average measurement.
Chapter 4
Figure 4.1
Trellis plot of oxygen saturation data.
Figure 4.2
Residual plot for logscale plasma volume data.
Figure 4.3
Trellis plot of log-scale vitamin D data.
Chapter 5
Figure 5.1
Trellis plot of kiwi data.
Figure 5.2
Trellis plot of oximetry data.
Figure 5.3
Plots for oximetry data. Top panel (left to right): Scatterplot with line of equality and Bland-Altman plot with zero line, with subject ID (1 to 61) as plotting symbol. Bottom panel (left to right): Same as top panel but with a common plotting symbol and points from the same subject joined by a broken line.
Figure 5.4
Plots for kiwi eggshell thickness data. Top panel (left to right): Scatterplot with line of equality and Bland-Altman plot with zero line based on 16 randomly formed measurement pairs. Bottom panel (left to right): Same as top panel but based on 16 average measurements.
Figure 5.5
Interaction plot for kiwi data depicting subject × method interaction. Lines join points from the same subject.
Figure 5.6
Interaction plots for oximetry data depicting subject × method interaction (left panel) and subject × time interaction (right panel). Lines join points from the same subject.
Figure 5.7
Residual plot for kiwi data.
Figure 5.8
Plots of residuals (top panel) and their absolute values (bottom panel) against fitted values for each separate method in oximetry data. A nonparametric smooth is added to the bottom plots.
Chapter 6
Figure 6.1
Trellis plot of cyclosporin data.
Figure 6.2
Plots for cyclosporin data. Panel (a): Bland-Altman plot with zero line. Panel (b): Plot of absolute values of centered differences against averages.
Figure 6.3
Trellis plot of cholesterol data.
Figure 6.4
Plots for cholesterol data. Top panel (left to right): Scatterplot with line of equality and Bland-Altman plot with zero line based on 100 randomly formed measurement pairs. Bottom panel (left to right): Same as top panel but based on average measurements.
Figure 6.5
Plots of standardized residuals (top panel) and their absolute values (bottom panel) against fitted values from a homoscedastic fit to cholesterol data.
Figure 6.6
Plots of log of absolute residuals from a homoscedastic fit to cholesterol data against log(
) (top panel) and
(bottom panel) with
as the average cholesterol level of a subject. A simple linear regression fit is superimposed on each plot.
Figure 6.7
Residual plots from a heteroscedastic fit to cholesterol data using power variance function models.
Figure 6.8
Observed versus fitted within-subject standard deviations from power (solid line) and exponential (broken curve) variance function models for cholesterol data. The covariate
, the subject average, is plotted on the horizontal axis. The observed values are represented by the points and the fitted values are represented by the curves.
Figure 6.9
95% limits of inter- and intra-method agreement for cholesterol data as a function of magnitude of measurement. The inter-method limits, based on the distribution of
D
, are centered at 5.58. The intra-method limits, based on the distributions of
D
1
and
D
2
, are centered at zero.
Figure 6.10
Plots for cholesterol data. (a) Estimate (solid curve) and 95% pointwise two-sided confidence band (broken curves) for precision ratio; (b) 95% lower confidence bands for inter- and intra-method versions of CCC; (c) 95% upper confidence bands for inter- and intra-method versions of TDI (0.90) as well as their reflections around the horizontal line at zero, giving the corresponding pointwise tolerance bands; and (d) same as panel (c) but with Ektachem recalibrated to have the same estimated mean as Cobas Bio.
Figure 6.11
A scatterplot of cyclosporin data with line of equality.
Figure 6.12
Plots of absolute standardized differences against averages for cyclosporin data with exponential and power variance function fits. A horizontal line at
is superimposed on each plot.
Figure 6.13
Plot of absolute centered differences against averages for cyclosporin data superimposed with
times fitted standard deviations of differences under power (solid line) and exponential (broken curve) variance function fits.
Figure 6.14
Estimate (solid curve) of the variance ratio for RIA over HPLC and its 95% pointwise confidence band (broken curves) for cyclosporin data.
Figure 6.15
95% pointwise bounds for cyclosporin data with (solid curve) and without (broken curve) the outlier. Panel (a): Lower confidence bounds for CCC. Panel (b): Upper confidence bounds for TDI and their reflections around the horizontal line at zero, giving pointwise tolerance bands.
Chapter 7
Figure 7.1
Trellis plot of systolic blood pressure data. The symbols for the four observers are given at the top of the plot.
Figure 7.2
Side-by-side boxplots for systolic blood pressure data.
Figure 7.3
A matrix of scatterplots with line of equality (below the diagonal) and Bland-Altman plots with zero line (above the diagonal) for systolic blood pressure data. The measurements range from 82 to 236 mm Hg and their differences range from −16 to 30 mm Hg.
Figure 7.4
Trellis plot of tumor size data. The symbols for the five readers are given at the top of the plot.
Figure 7.5
Side-by-side boxplots for tumor size data.
Figure 7.6
Interaction plot for tumor size data depicting lesion × reader interaction.
Figure 7.7
A matrix of scatterplots with line of equality (below the diagonal) and BlandAltman plots with zero line (above the diagonal) for tumor size data. One measurement from each reader on every subject is randomly selected for this plot. The measurements range from 1 to 9 cm and their differences range from 3 to 4 cm.
Figure 7.8
Residual plot for systolic blood pressure data.
Figure 7.9
Residual plot for tumor size data.
Chapter 8
Figure 8.1
Trellis plots of blood pressure data by gender.
Figure 8.2
Side-by-side boxplots for blood pressure data by gender.
Figure 8.3
Scatterplots of blood pressure against age (left panel) and against heart rate (right panel).
Figure 8.4
Plots for blood pressure data. Top panel (left to right): Scatterplot with line of equality and Bland-Altman plot with zero line based on randomly formed measurement pairs. Bottom panel (left to right): Same as top panel but based on average measurements.
Figure 8.5
Plots of log of absolute residuals from a homoscedastic fit to blood pressure data against log(
) with
as subject average blood pressure. A simple linear regression fit is superimposed on each plot.
Figure 8.6
Residual plots from a heteroscedastic fit to blood pressure data using power variance function models.
Figure 8.7
Estimates and two-sided 95% simultaneous confidence bands for the precision ratio λ12 under Models A and B.
Figure 8.8
Figure 8.8 One-sided 95% simultaneous confidence bands for TDI(0.90) and CCC—lower bands for CCC and upper bands for TDI—and their intra-method versions for mercury (method 1) and automatic (method 2) methods.
Chapter 9
Figure 9.1
Trajectories of percentage body fat measurements for 112 girls. Lines connect the available time points from the same subject. The gray curves in the middle are the estimated mean functions.
Figure 9.2
Trajectories of DEXA minus caliper differences in percentage body fat measurements for 91 girls with complete measurement pairs. Lines connect the available time points from the same subject. The gray curve in the middle is the estimated mean difference function.
Figure 9.3
Side-by-side boxplots of DEXA minus caliper differences in percentage body fat measurements for visit numbers two through nine, with a reference line at zero.
Figure 9.4
Scatterplots of percentage body fat measurements for visit numbers two (bottom left panel) through nine (top right panel). The line of equality is superimposed on each plot.
Figure 9.5
Bland-Altman plots of percentage body fat measurements for visit numbers two (bottom left panel) through nine (top right panel) for available pairs. A horizontal line at zero is superimposed on each plot.
Figure 9.6
Estimated semivariogram functions for caliper and DEXA methods computed using standardized residuals from a model fit to percentage body fat data with independent within-subject errors. A nonparametric smooth curve is added to each plot to show the underlying trend.
Figure 9.7
Sample autocorrelation functions for normalized residuals of caliper and DEXA methods under a model fit to percentage body fat data with AR(1) errors. The dashed curves represent the 95% bounds (9.19).
Figure 9.8
Estimate of mean difference in percentage body fat using caliper and DEXA methods (solid curve), its 95% two-sided simultaneous confidence band (shaded region), and the 95% limits of agreement (broken curves).
Figure 9.9
Estimates of CCC and TDI functions (solid curves) and their 95% onesided simultaneous confidence bands (shaded regions) for percentage body fat data.
Chapter 10
Figure 10.1
Trellis plot of unreplicated blood pressure data.
Figure 10.2
A scatterplot with line of equality (left panel) and a Bland-Altman plot with zero line (right panel) for unreplicated blood pressure data.
Figure 10.3
Side-by-side boxplots for unreplicated blood pressure data.
Figure 10.4
Trellis plot of replicated blood pressure data.
Figure 10.5
A matrix of scatterplots of systolic blood pressures with line of equality (below the diagonal) and Bland-Altman plots with zero line (above the diagonal) for replicated blood pressure data. One measurement per method from each of the 85 subjects is randomly selected for this plot. The measurements range from 76 to 227 mm Hg and their differences range from −25 to 111 mm Hg.
Figure 10.6
Side-by-side box plots for all measurements of replicated blood pressure data.
Chapter 11
Figure 11.1
Expected standard errors for estimators of log{TDI(0.90)} (left panel) and
z
(CCC) (right panel) as functions of
n
for a paired measurements design.
Chapter 12
Figure 12.1
Bangdiwala agreement chart for the MS data in Table 12.3.
Figure 12.2
Range of
κ
values for a given probability of agreement
θ
. Given
θ
= 0.8,
κ
cannot exceed 0.6; even when
θ
is as high as 0.90,
κ
cannot exceed 0.8, and can be negative.
Pages
ii
iii
iv
v
xv
xvi
xvii
1
2
3
4
5
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
89
90
91
93
94
95
96
97
98
99
100
103
105
106
107
108
109
110
111
112
113
114
115
116
118
119
121
122
125
126
127
128
130
131
132
133
134
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
Add Highlight
No Comment
..................Content has been hidden....................
You can't read the all page of ebook, please click
here
login for view all page.
Day Mode
Cloud Mode
Night Mode
Reset