Contents

Preface

Acknowledgments

1     Introduction

1.1     Controversies

1.2     A guided tour of decision theory

Part One   Foundations

2     Coherence

2.1     The “Dutch Book” theorem

2.1.1     Betting odds

2.1.2     Coherence and the axioms of probability

2.1.3     Coherent conditional probabilities

2.1.4     The implications of Dutch Book theorems

2.2     Temporal coherence

2.3     Scoring rules and the axioms of probabilities

2.4     Exercises

3     Utility

3.1     St. Petersburg paradox

3.2     Expected utility theory and the theory of means

3.2.1     Utility and means

3.2.2     Associative means

3.2.3     Functional means

3.3     The expected utility principle

3.4     The von Neumann–Morgenstern representation theorem

3.4.1     Axioms

3.4.2     Representation of preferences via expected utility

3.5     Allais’ criticism

3.6     Extensions

3.7     Exercises

4     Utility in action

4.1     The “standard gamble”

4.2     Utility of money

4.2.1     Certainty equivalents

4.2.2     Risk aversion

4.2.3     A measure of risk aversion

4.3     Utility functions for medical decisions

4.3.1     Length and quality of life

4.3.2     Standard gamble for health states

4.3.3     The time trade-off methods

4.3.4     Relation between QALYs and utilities

4.3.5     Utilities for time in ill health

4.3.6     Difficulties in assessing utility

4.4     Exercises

5     Ramsey and Savage

5.1     Ramsey’s theory

5.2     Savage’s theory

5.2.1     Notation and overview

5.2.2     The sure thing principle

5.2.3     Conditional and a posteriori preferences

5.2.4     Subjective probability

5.2.5     Utility and expected utility

5.3     Allais revisited

5.4     Ellsberg paradox

5.5     Exercises

6     State independence

6.1     Horse lotteries

6.2     State-dependent utilities

6.3     State-independent utilities

6.4     Anscombe–Aumann representation theorem

6.5     Exercises

Part Two   Statistical Decision Theory

7     Decision functions

7.1     Basic concepts

7.1.1     The loss function

7.1.2     Minimax

7.1.3     Expected utility principle

7.1.4     Illustrations

7.2     Data-based decisions

7.2.1     Risk

7.2.2     Optimality principles

7.2.3     Rationality principles and the Likelihood Principle

7.2.4     Nuisance parameters

7.3     The travel insurance example

7.4     Randomized decision rules

7.5     Classification and hypothesis tests

7.5.1     Hypothesis testing

7.5.2     Multiple hypothesis testing

7.5.3     Classification

7.6     Estimation

7.6.1     Point estimation

7.6.2     Interval inference

7.7     Minimax–Bayes connections

7.8     Exercises

8     Admissibility

8.1     Admissibility and completeness

8.2     Admissibility and minimax

8.3     Admissibility and Bayes

8.3.1     Proper Bayes rules

8.3.2     Generalized Bayes rules

8.4     Complete classes

8.4.1     Completeness and Bayes

8.4.2     Sufficiency and the Rao–Blackwell inequality

8.4.3     The Neyman–Pearson lemma

8.5     Using the same α level across studies with different sample sizes is inadmissible

8.6     Exercises

9     Shrinkage

9.1     The Stein effect

9.2     Geometric and empirical Bayes heuristics

9.2.1     Is x too big for θ?

9.2.2     Empirical Bayes shrinkage

9.3     General shrinkage functions

9.3.1     Unbiased estimation of the risk of x + g(x)

9.3.2     Bayes and minimax shrinkage

9.4     Shrinkage with different likelihood and losses

9.5     Exercises

10   Scoring rules

10.1   Betting and forecasting

10.2   Scoring rules

10.2.1   Definition

10.2.2   Proper scoring rules

10.2.3   The quadratic scoring rules

10.2.4   Scoring rules that are not proper

10.3   Local scoring rules

10.4   Calibration and refinement

10.4.1   The well-calibrated forecaster

10.4.2   Are Bayesians well calibrated?

10.5   Exercises

11   Choosing models

11.1   The “true model” perspective

11.1.1   Model probabilities

11.1.2   Model selection and Bayes factors

11.1.3   Model averaging for prediction and selection

11.2   Model elaborations

11.3   Exercises

Part Three   Optimal Design

12   Dynamic programming

12.1   History

12.2   The travel insurance example revisited

12.3   Dynamic programming

12.3.1   Two-stage finite decision problems

12.3.2   More than two stages

12.4   Trading off immediate gains and information

12.4.1   The secretary problem

12.4.2   The prophet inequality

12.5   Sequential clinical trials

12.5.1   Two-armed bandit problems

12.5.2   Adaptive designs for binary outcomes

12.6   Variable selection in multiple regression

12.7   Computing

12.8   Exercises

13   Changes in utility as information

13.1   Measuring the value of information

13.1.1   The value function

13.1.2   Information from a perfect experiment

13.1.3   Information from a statistical experiment

13.1.4   The distribution of information

13.2   Examples

13.2.1   Tasting grapes

13.2.2   Medical testing

13.2.3   Hypothesis testing

13.3   Lindley information

13.3.1   Definition

13.3.2   Properties

13.3.3   Computing

13.3.4   Optimal design

13.4   Minimax and the value of information

13.5   Exercises

14   Sample size

14.1   Decision-theoretic approaches to sample size

14.1.1   Sample size and power

14.1.2   Sample size as a decision problem

14.1.3   Bayes and minimax optimal sample size

14.1.4   A minimax paradox

14.1.5   Goal sampling

14.2   Computing

14.3   Examples

14.3.1   Point estimation with quadratic loss

14.3.2   Composite hypothesis testing

14.3.3   A two-action problem with linear utility

14.3.4   Lindley information for exponential data

14.3.5   Multicenter clinical trials

14.4   Exercises

15   Stopping

15.1   Historical note

15.2   A motivating example

15.3   Bayesian optimal stopping

15.3.1   Notation

15.3.2   Bayes sequential procedure

15.3.3   Bayes truncated procedure

15.4   Examples

15.4.1   Hypotheses testing

15.4.2   An example with equivalence between sequential and fixed sample size designs

15.5   Sequential sampling to reduce uncertainty

15.6   The stopping rule principle

15.6.1   Stopping rules and the Likelihood Principle

15.6.2   Sampling to a foregone conclusion

15.7   Exercises

Appendix

A.1     Notation

A.2     Relations

A.3     Probability (density) functions of some distributions

A.4     Conjugate updating

References

Index

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