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by Gregory Stephanopoulos, Jens Nielsen, Sang Yup Lee, Ho Nam Chang
Emerging Areas in Bioengineering
Cover
Related Titles
Title Page
Copyright
List of Contributors
About the Series Editors
Part I: Biocatalysis
Chapter 1: Introduction to Emerging Areas in Bioengineering
1.1 Biotechnology
1.2 Bioengineering
1.3 Emerging Areas
1.4 Current Volume
Acknowledgments
References
Chapter 2: Over-Expression of Functionally Active Inclusion Bodies of Enzymes in Recombinant Escherichia coli
2.1 Introduction
2.2 Formation and Composition of IBs
2.3 Enhancement of Protein Quality and Enzymatic Activity in IBs
2.4 Applications of Enzyme-Based IBs
2.5 An Example of IBs: N-acetyl-d-neuraminic Acid Aldolase
2.6 Concluding Remarks
Acknowledgments
References
Chapter 3: Enzymatic Reactions in Ionic Liquids
3.1 Introduction
3.2 Enzymatic Reactions in Ionic Liquids
3.3 Factors Affecting Enzymatic Reactions in Ionic Liquids
3.4 Methods to Improve Enzyme Activity and Stability in Ionic Liquids
3.5 Conclusions and Perspectives
Abbreviations of Ionic Liquids
References
Chapter 4: Enzyme Immobilization on Nanoparticles: Recent Applications
4.1 Introduction
4.2 Preparation of Enzyme-Immobilized Nanoparticles
4.3 Application of Enzyme Nanoparticles
4.4 Conclusion and Perspectives
References
Chapter 5: Whole Cell Biocatalysts Using Enzymes Displayed on Yeast Cell Surface
Concise Definition of Subject
5.1 Introduction
5.2 GPI-Anchoring System
5.3 C-Terminus Free Display Systems
5.4 Applications of the Yeast Cell Surface Display System for Biocatalysts
5.5 Improvement of Catalytic Activity on the Yeast Cell Surface
5.6 Conclusions
References
Chapter 6: Design of Artificial Supramolecular Protein Assemblies by Enzymatic Bioconjugation for Biocatalytic Reactions
Concise Definition of Subject
6.1 Introduction
6.2 Protein Assembly on a Template with Specific Interaction/Reaction Sites
6.3 Protein Assembly without a Template: Self-Assembly of Protein Units
6.4 Future Prospects
Acknowledgment
Conflict of Interest
References
Chapter 7: Production of Valuable Phenolic Compounds from Lignin by Biocatalysis: State-of-the-Art Perspective
7.1 Lignin and Its Composition
7.2 Phenol Derivatives Derived from Lignin Deconstruction
7.3 Biocatalysis to Increase the Value of Lignin-Derived Phenolic Compounds
7.4 Outlook and Future Perspectives
Acknowledgments
References
Part II: Biofuels and Renewable Energy from Biomass
Chapter 8: Biofuels, Bio-Power, and Bio-Products from Sustainable Biomass: Coupling Energy Crops and Organic Waste with Clean Energy Technologies
8.1 Introduction
8.2 Sustainable Biomass for Sustainable Development
8.3 Biorefineries and Bioenergy Conversion Pathways
8.4 Conclusions
References
Further Reading/Resources
Chapter 9: Potential Lignocellulosic Biomass Resources in ASEAN Countries
9.1 Introduction and Characterization of Lignocellulosic Biomass in ASEAN Countries
9.2 Forest Residues in ASEAN Countries
9.3 Herbaceous Plants Residues in ASEAN Countries
9.4 Agriculture Residue in ASEAN Countries
9.5 ASEAN Government Programs and Policies on Natural Biomass
References
Chapter 10: Volatile Fatty Acid Platform: Concept and Application
10.1 Concept of Volatile Fatty Acid Platform
10.2 Application of VFA Platform
10.3 Tasks for Commercialization
References
Chapter 11: Biological Pretreatment of Lignocellulosic Biomass for Volatile Fatty Acid Production
11.1 Introduction
11.2 Pretreatments to Improve VFA Production
11.3 Future Prospect and Recent Technology Development
References
Chapter 12: Microbial Lipid Production from Volatile Fatty Acids by Oleaginous Yeast
12.1 Introduction
12.2 VFAs as a Carbon Source
12.3 Quality of Yeast Lipid
12.4 Conclusion
Acknowledgments
References
Chapter 13: Gasification Technologies for Lignocellulosic Biomass
13.1 Introduction
13.2 Gasification of Lignocellulosic Biomass
13.3 Overview of Gasification Technologies of Lignocellulosic Biomass
13.4 Classification of Gasification Technologies
13.5 Types of Gasification Systems
13.6 Performance Evaluation of Biomass Gasifiers
13.7 Industrial Biomass Gasification Plants
13.8 Conclusion
References
Chapter 14: Separation of Butanol, Acetone, and Ethanol
14.1 Gas Stripping
14.2 Liquid–Liquid Extraction
14.3 Adsorption
14.4 Pervaporation
14.5 Distillation
14.6 Conclusion
References
Chapter 15: Overview of Microalgae-Based Carbon Capture and Utilization
15.1 Introduction
15.2 Capturing of Inorganic Carbon Using Photosynthesis
15.3 Microalgal Biofuel Production
15.4 Application of Microalgal By-Products
15.5 Conclusion
References
Chapter 16: Bioengineering of Microbial Fuel Cells: From Extracellular Electron Transfer Pathway to Electroactive Biofilm
16.1 Microbial Fuel Cells: General Concept and Extracellular Electron Transfer
16.2 Electroactive Biofilm Meets with Biocompatible Materials
16.3 Bioengineering of Electroactive Biofilm: From Bacteria to Ecosystem
16.4 Conclusions and Future Perspectives
Acknowledgments
References
Part III: Synthetic Biology and Metabolic Engineering
Chapter 17: Genome Editing Tools for Escherichia coli and Their Application in Metabolic Engineering and Synthetic Biology
17.1 Introduction
17.2 Homologous Recombination-Mediated Tools
17.3 Single-Strand DNA-Mediated Recombination
17.4 Conclusion
References
Chapter 18: Synthetic Biology for Corynebacterium glutamicum: An Industrial Host for White Biotechnology
18.1 Introduction
18.2 Synthetic Elements of Synthetic Biology for C. glutamicum
18.3 Conclusion and Outlook
References
Chapter 19: Metabolic Engineering of Solventogenic Clostridia for Butanol Production
19.1 Introduction
19.2 Biomass and Its Metabolism
19.3 Metabolic Engineering of Clostridia
19.4 Concluding Remarks and Future Perspectives
References
Chapter 20: Metabolic Engineering of Microorganisms for the Production of Lactate-Containing Polyesters
Acknowledgments
References
Chapter 21: Microbial Metabolic Engineering for Production of Food Ingredients
21.1 Metabolic Engineering
21.2 Biological Production of Functional Food Materials
21.3 Future Prospects
References
Part IV: Products
Chapter 22: Application of Lactic Acid Bacteria for Food Biotechnology
Concise Definition of Subject and Its Importance
22.1 Lactic Acid Bacteria
22.2 Expression Systems in LAB
22.3 In silico Metabolic Pathway Model for LAB
22.4 The Prospect: Lactic Acid Bacteria as an Edible Therapeutic Probiotics
References
Chapter 23: Biopolymers Based on Raw Materials from Biomass
23.1 Introduction
23.2 Poly(butylene succinate)
23.3 Conclusion
References
Chapter 24: Bacterial Biofertilizers: High Density Cultivation
24.1 Introduction
24.2 Cultivation Strategies for a Few Important Bacterial Inoculants
Conflict of Interest
References
Part V: Biosensing and Nanobiotechnology
Chapter 25: Current Research in Korean Herbal Cosmetics
25.1 Introduction
25.2 Korean Herbal Medicine and Bioscience
25.3 Bioprocessing of Natural Compounds in Traditional Herbal Medicine
25.4 Skin Delivery Systems in Cosmetics
25.5 Conclusions
References
Chapter 26: Advanced Genetic Engineering of Microbial Cells for Biosensing Applications
26.1 Introduction
26.2 Genetic Engineering of Microbial Reporter Cells
26.3 Methods to Immobilize Cells and Maintain Cell Viability
26.4 Microbial Biosensors Based on Transducers
26.5 Conclusion and Future Prospects
Acknowledgments
References
Chapter 27: Bioelectronic Nose
27.1 Introduction
27.2 Concept of Bioelectronic Nose
27.3 Primary Transducer for Bioelectronic Nose
27.4 Secondary Transducer for Bioelectronic Nose
27.5 Applications
27.6 Conclusion
Acknowledgment
References
Chapter 28: Noninvasive Optical Imaging Techniques in Clinical Application
28.1 Fluorescence Diagnosis of Skin or Mucosa
28.2 Fluorescence Endoscopic Surgery
28.3 Fluorescence Image-Guided Intraoperative Open Surgery
28.4 Conclusion
Acknowledgments
References
Chapter 29: Advanced Short Tandem Repeat Genotyping for Forensic Human Identification
29.1 DNA Sample Sources and Collection
29.2 DNA Extraction from Biological Sources
29.3 Short Tandem Repeat Markers and Commercial Kits
29.4 Amplification of STR Loci
29.5 Capillary Electrophoretic Separation of STR Amplicons
29.6 Total Integrated Forensic STR Typing System
29.7 Conclusion
References
Chapter 30: DNA Microarray-Based Technologies to Genotype Single Nucleotide Polymorphisms
30.1 Allele-Specific Oligonucleotide Competitive Hybridization (ASOCH)
30.2 Zip-Code Microarray
30.3 Universal Amplification-Based Technology
30.4 Bead Array Platform-Based SNP Genotyping
30.5 Conclusion
References
Chapter 31: Advanced Applications of Nanoscale Measuring System for Biosensors
Chapter Outline
31.1 Nanoscale Gravimetric Measuring System for Chiral Recognition
31.2 Nanoscale Measuring System Using Two-Photon-Adsorbed Photopolymerization for Biosensors
31.3 Nanoscale Measuring Systems Using AFM for Biosensors
31.4 Nanoscale Measuring Systems with Nanoscale Motion Detection
References
Chapter 32: Biosynthesis and Applications of Silver Nanoparticles
Concise Definition of Subject
32.1 Introduction
32.2 Silver Nanoparticles
32.3 Plants in Nanoparticle Synthesis
32.4 Parameters Affecting Synthesis of AgNPs
32.5 Mechanism of AgNP Synthesis
32.6 Applications of AgNPs
32.7 Conclusion
References
Part VI: Biomedical Engineering and Biopharmaceuticals
Chapter 33: Smart Drug Delivery Devices and Implants
33.1 Introduction
33.2 External Drug Delivery Devices
33.3 Internal Drug Delivery Implants
33.4 Image-Guided Drug Delivery Systems
33.5 Summary and Perspectives
Acknowledgments
References
Chapter 34: Controlled Delivery Systems of Protein and Peptide Therapeutics
34.1 Introduction
34.2 Drug Delivery Systems for Protein and Peptide Therapeutics
34.3 Clinical Development of Protein and Peptide Delivery Systems
34.4 Summary and Perspectives
References
Chapter 35: Cell Delivery Systems Using Biomaterials
35.1 Introduction to Cell-Based Therapeutics
35.2 Biomaterials as Cell Delivery Vehicles
35.3 Cell Delivery Strategies
35.4 Conclusion and Future Perspective
References
Chapter 36: Bioengineered Cell-Derived Vesicles as Drug Delivery Carriers
36.1 Introduction
36.2 Prokaryotic Cell-Derived Nanocarriers
36.3 Eukaryotic Cell-Derived Nanocarriers
36.4 Cell Membrane-Camouflaged Nanoparticles
36.5 Conclusions
Acknowledgments
References
Chapter 37: Advanced Genetic Fusion Techniques for Improving the Pharmacokinetic Properties of Biologics
Concise Definition of the Subject
37.1 Background
37.2 Fc-Fusion Technology
37.3 Albumin Fusion Technology
37.4 Transferrin Fusion Technology
37.5 CTP Fusion Technology
37.6 Summary
References
Chapter 38: Mussel-Mimetic Biomaterials for Tissue Engineering Applications
38.1 Introduction
38.2 Synthetic and Natural Polymer-Based Mussel-Mimetic Biomaterials
38.3 Tissue Adhesives
38.4 Biomolecule Immobilization and Drug Delivery
38.5 Concluding Remarks
Acknowledgments
References
Chapter 39: Mass Production of Full-Length IgG Monoclonal Antibodies from Mammalian, Yeast, and Bacterial Hosts
39.1 Mass Production of Biosimilar Monoclonal Antibodies in Mammalian Cells
39.2 Mass Production of Monoclonal Antibodies in Yeast
39.3 Mass Production of Monoclonal Antibodies in Escherichia coli
39.4 Conclusion
References
Chapter 40: Recent Advances in Mass Spectrometry-Based Proteomic Methods for Discovery of Protein Biomarkers for Complex Human Diseases
Concise Definition of Subject
40.1 Introduction
40.2 MS-Based Proteomic Analysis Pipeline for Discovery of Protein Biomarkers
40.3 Discovery of Protein Biomarkers Using LC–MS/MS Analysis
40.4 Analysis of Proteomic Data for the Biomarker Discovery
40.5 Verification and Validation of Biomarker Candidates
References
Part VII: Computer-Aided Bioprocess Design and Systems Biology
Chapter 41: Overview on Bioprocess Simulation
41.1 Introduction
41.2 Modeling and Design of Bioprocess
41.3 Monitoring of Bioprocess
41.4 Control of Bioprocess
41.5 Computational Fluid Dynamics in Bioprocess Simulation
References
Chapter 42: Bioprocess Simulation and Scheduling
42.1 The Purpose of Bioprocess Simulation
42.2 Detailed Modeling of Single Batch Bioprocesses
42.3 Design and Operation of Multiproduct Facilities
42.4 Conclusion
Abbreviations
References
Chapter 43: Metabolism-Combined Growth Model Construction and Its Application to Optimal Bioreactor Operation
43.1 Introduction
43.2 Growth Model Construction and a Diversity of Modification Methods
43.3 Optimal Decision-Making System
43.4 Case Study
43.5 Summary
Acknowledgments
References
Chapter 44: Software Applications for Phenotype Analysis and Strain Design of Cellular Systems
44.1 Introduction
44.2 COBRA Framework
44.3 COBRA Software Applications
44.4 Utilizing the Potential of COBRA Software Applications Suite: A Practical Case Study
44.5 Conclusions and Future Perspectives
References
Chapter 45: Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions
45.1 Biological Computer-Aided Design of Interactions
45.2 Community Metabolic Network Reconstruction
45.3 Prediction of Interactions Using Metabolic Networks
45.4 Conclusions
Acknowledgments
Conflicts of Interest
References
Index
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Edited by Ho Nam Chang
Emerging Areas in Bioengineering
Volume 1
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