- Title Page
- Foreword
- Preface
- Part I: Hydrodynamic Flow Confinement (HFC)
- Chapter 1: Hydrodynamic Flow Confinement Using a Microfluidic Probe
- Chapter 2: Hierarchical Hydrodynamic Flow Confinement (hHFC) and Recirculation for Performing Microscale Chemistry on Surfaces
- Chapter 3: Design of Hydrodynamically Confined Microflow Devices with Numerical Modeling: Controlling Flow Envelope, Pressure, and Shear Stress
- Chapter 4: Hele-Shaw Flow Theory in the Context of Open Microfluidics: From Dipoles to Quadrupoles
- Chapter 5: Implementation and Applications of Microfluidic Quadrupoles
- Chapter 6: Hydrodynamic Flow Confinement-Assisted Immunohistochemistry from Micrometer to Millimeter Scale
- Chapter 7: Local Nucleic Acid Analysis of Adherent Cells
- Chapter 8: Microfluidic Probe for Neural Organotypic Brain Tissue and Cell Perfusion
- Chapter 9: The Multifunctional Pipette
- Chapter 10: Single-Cell Analysis with the BioPen
- Chapter 11: Microfluidic Probes for Single-Cell Proteomic Analysis
- 11.1 Introduction
- 11.2 Technical Requirements of Single-Cell Proteomic Analysis
- 11.3 Methods for Single-Cell Proteomic Analysis
- 11.4 Microfluidics Enabling Next-Generation Single-Cell Proteomics
- 11.5 Open-Ended Microwells for Proteomic and Multiparameter Single-Cell Studies
- 11.6 Microfluidic Probes in In Situ Single-Cell Proteomic Measurement
- 11.7 Outlook for Future Work with Microfluidic Single-Cell Proteomic Assay
- 11.8 Conclusion
- References
- Part II: Localized Chemistry
- Chapter 12: Aqueous Two-Phase Systems for Micropatterning of Cells and Biomolecules
- Chapter 13: Development of Pipettes as Mobile Nanofluidic Devices for Mass Spectrometric Analysis
- 13.1 Introduction
- 13.2 Segmented Flow Analysis
- 13.3 Utility of Nano- and Micropipettes in Mass Spectrometry
- 13.4 Development of Nanopipette Probes for Local Sampling
- 13.5 MALDI-MS Analysis of Analyte Post-Nanopipette Sampling
- 13.6 Development of Segmented Flow Sampling
- 13.7 Study of Intercellular Heterogeneity
- 13.8 Conclusion and Outlook
- Acknowledgments
- References
- Chapter 14: FluidFM: Development of the Instrument as well as Its Applications for 2D and 3D Lithography
- Chapter 15: FluidFM Applications in Single-Cell Biology
- Chapter 16: Soft Probes for Scanning Electrochemical Microscopy
- Chapter 17: Microfluidic Probes for Scanning Electrochemical Microscopy
- Chapter 18: Chemistrode for High Temporal- and Spatial-Resolution Chemical Analysis
- 18.1 Introduction
- 18.2 Chemistrode Design and Operation
- 18.3 Physical Principles Governing the Transport Processes
- 18.4 Multiform Chemical Analysis Independent in Space and Time from Data Acquisition
- 18.5 Applicability for Stimuli–Response Surfaces
- 18.6 Challenges and Future Directions
- Acknowledgments
- References
- Index
- End User License Agreement
Open-Space Microfluidics
Concepts, Implementations, Applications
Edited by Emmanuel Delamarche and Govind V. Kaigala
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