Chapter 13. Reliability and Validity: Assessing the Psychometric Properties of Rating Scales

Douglas Faries Ilker Yalcin^[]

^[] Douglas Faries is Research Advisor, Global Statistical Sciences, Eli Lilly and Company, USA. Ilker Yalcin is Manager, Commercialization Information Sciences, Eli Lilly and Company, USA.

Using outcome measures that are reliable and valid is a prerequisite to quality clinical research. In this chapter, statistical approaches for assessing the reliability and validity of an outcome measure are presented and discussed. In addition to the general concepts, examples from multiple clinical experiments utilizing a variety of outcome measures are provided.