SuperFetch analyzes desktop usage patterns and pre-populates system RAM with the programs the user is most likely to use. When using non-persistent desktops, this results in unnecessary storage I/O, as the optimizations will not persist and will be repeated each time the desktop is used. Additionally, SuperFetch also allocates additional system RAM for its use, which increases the amount of per-desktop RAM required.

For persistent Horizon desktops that also have larger amounts of RAM, you should leave SuperFetch enabled so that Windows can optimize the disk layout of the prefetch data and proactively load user binaries into RAM. This will make the desktop more responsive, and, since the desktop is persistent, the SuperFetch optimizations will persist across Horizon client sessions.