The VMware Horizon Agent supports multiple versions of the Microsoft Windows desktop OS and Microsoft Windows (RDS) Server. The following table outlines which Windows OSes are currently supported.
| Windows OS Version | Product Edition | Service Pack | Notes |
| Windows 10 (32-bit or 64-bit) | Support varies based on build | None | Consult VMware KB 2149393 (link below) |
| Windows 8.1 (32-bit or 64-bit) | Enterprise or Professional | Latest update | Instant Clones not supported |
| Windows 7 (32-bit or 64-bit) | Enterprise or Professional | SP1 | Full support |
| Windows 2016 (64-bit) | Standard or Datacenter | Latest update | Full support |
| Windows 2012 R2 (64-bit) | Standard or Datacenter | Latest update | Full support (RDS host or desktop) |
| Windows 2012 (64-bit) | Datacenter | None | As RDS host only |
| Windows 2008 R2 (64-bit) | Datacenter | SP1 | Full support (RDS host or desktop) |
To obtain current information about which desktop OSes and Microsoft RDS server versions are supported, please refer to VMware KB articles 2149393 (https://kb.vmware.com/s/article/2149393), 2150305 (https://kb.vmware.com/s/article/2150305), and 2150295 (https://kb.vmware.com/s/article/2150295).