Calculating the sample size for a 1-Sample equivalence test

The power and sample size tools enable us to calculate the number of samples we require to prove that a test sample is equivalent to a target or another sample.

Here, we check the number of samples required to prove that a batch of syringes have a fill volume with a mean of 15 ml. To be equivalent, the mean fill volume should be within +/- 0.25 of the target. The goal is to be able to identify that the mean is less than 0.1 different to the target, with at least 80 percent or 90 percent power.

We will use a standard deviation of 0.27 for this study.

Getting Ready

We will not open a dataset for this study. This example follows the previous recipe, Using equivalence tests to prove zero difference between the mean and a target.

How to do it…

The following steps will calculate a sample size required to check for equivalence with at least 80 percent power:

  1. Navigate to Stat | Power and Sample Size | Equivalence Tests | 1-Sample….
  2. Set Lower limit: to -0.25 and Upper limit: to 0.25.
  3. Enter Differences (within the limits): as 0.1.
  4. Enter Power values: as .8 .9.
  5. Enter Standard deviation: of 0.27.
  6. Click on OK.

How it works…

The difference within the limits is the size of difference that we want to be able to declare is equivalent 80 percent or 90 percent. For example, if the mean is .1 different to the target, we will want to know how many samples are required to prove that this result is equivalent with 80 percent or 90 percent power.

The equivalent limits are the range within which the confidence interval must fall to be able to prove that the mean is no further away than the equivalence limit.

See also

  • The Using equivalence tests to prove zero difference between the mean and a target recipe
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